AIC Seminar Series
Proteome Analyst: A web-based tool for Predicting Properties of Proteins
|Russell Greiner||University of Alberta||[Home Page]|
Notice: Hosted by Vinay Chaudhri. Note the non-usual day (Tuesday)
Date: Tuesday, February 23rd 2010 at 4:00pm
Location: EJ228 (SRI E building) (Directions)
Proteome Analyst (PA) is a publicly available, high-throughput, web-based system for predicting various properties of each protein in an entire proteome. Using machine-learned classifiers, PA can predict, for example, the GeneQuiz general function and Gene Ontology (GO) molecular function of a protein. In addition, PA is one of the most accurate and most comprehensive systems for predicting subcellular localization, the location within a cell where a protein performs its main function. Two other capabilities of PA are notable. First, PA can create a custom classifier to predict a new property, without requiring any programming, based on labeled training data (i.e. a set of examples, each with the correct classification label) provided by a user. PA has been used to create custom classifiers for potassium-ion channel proteins and other general function ontologies. Second, PA provides a sophisticated explanation feature that shows why one prediction is chosen over another. The PA system produces a Naive Bayes classifier, which is amenable to a graphical and interactive approach to explanations for its predictions; transparent predictions increase the users confidence in, and understanding of, PA.
Please arrive at least 10 minutes early as you will need to sign in by
following instructions by the lobby phone at Building E (or call Wilma
Lenz at 650 859 4904, or Vicenta at Lopez at 650 859 5750). SRI is
located at 333 Ravenswood Avenue in Menlo Park. Visitors may park in the
parking lots off Fourth Street. Detailed directions to SRI, as well as maps,
are available from the Visiting AIC web page.
There are two entrances to SRI International located on Ravenswood Ave.
Please check the Building E entrance signage.
©2017 SRI International 333 Ravenswood Avenue, Menlo Park, CA 94025-3493