EcoCyc: Electronic Encyclopedia of E. coli Genes and Metabolism
by Karp, P. and Riley, M. and Paley, S. and Pellegrini-Toole, A.
Nuc. Acids Res., vol. 24, no. 1, pp. 32–39, 1996.
The Encyclopedia of E. coli Genes and Metabolism (EcoCyc) is a database that combines information about the genome and the intermediary metabolism of E. coli. It describes 2034 genes of E. coli, 306 enzymes encoded by these genes, 580 metabolic reactions that occur in E. coli, and the organization of these reactions into 100 metabolic pathways. The EcoCyc graphical user interface allows scientists to query and explore the EcoCyc database using visualization tools such as genomic-map browsers and automatic layouts of metabolic pathways. EcoCyc spans the space from sequence to function to allow scientists to investigate an unusually broad range of questions. EcoCyc can be thought of as both an electronic review article because of its copious references to the primary literature, and as an in silico model of E. coli that can be probed and analyzed through computational means.
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| Name | Title | ||
|---|---|---|---|
| Karp, Peter D | Director, Bioinformatics Research Group |  |
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Paley, Suzanne | Computer Scientist | |
