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The BioCyc Database Collection is a collection of Pathway/Genome Databases. Each database in the BioCyc collection describes the genome and metabolic pathways of a single organism.
MetaCyc is a database of nonredundant, experimentally elucidated metabolic pathways. MetaCyc contains more than 1800 pathways from more than 2200 different organisms (circa 2012). The MetaCyc data were curated from more than 33,000 scientific publications. MetaCyc describes metabolic pathways, reactions, enzymes, and metabolites.
The following publications are selected by the author. They are listed in reverse chronological order.
[View All 8 Publications]
Caspi R, Dreher K and Karp PD. The challenge of constructing, classifying, and representing metabolic pathways. FEMS Microbiol Lett., vol. 45, no. 2, pp. 85-93, August 2013. [Details]
Caspi R, Altman T, Dreher K, Fulcher CA, Subhraveti P, Keseler IM, Kothari A, Krummenacker M, Latendresse M, Mueller LA, Ong Q, Paley S, Pujar A, Shearer AG, Travers M, Weerasinghe D, Zhang P, Karp PD. The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases. Nucleic Acids Res, vol. 40, no. D1, pp. D742-D753, 2012. [PDF, Details]
Karp P.D., Caspi R. A survey of metabolic databases emphasizing the MetaCyc family. Arch Toxicol, vol. 85, pp. 1015-33, 2011. [Details]